Frequently Asked Questions About XARELTO®
Answers to frequently asked questions about XARELTO® for people with atrial fibrillation (AFib), deep vein thrombosis (DVT), or pulmonary embolism (PE), and those who’ve had knee or hip replacement surgery.
What makes XARELTO® selective?
Warfarin interferes with vitamin K and at least six blood-clotting factors. XARELTO® targets one critical factor of your body’s natural clotting function. And it has similar effectiveness to warfarin. XARELTO® also doesn’t require regular blood monitoring to check your blood-thinning level. And there are no known dietary restrictions, so you can continue to eat a range of healthy foods when taking XARELTO®.
Why doesn’t XARELTO® require regular blood monitoring?
XARELTO® has been shown to deliver a predictable blood-thinning (anticoagulant) effect. In clinical studies, involving more than 55,000 people, regular blood monitoring was not required. So you won’t need to schedule around regular blood tests to see if it’s working, check your levels, or change your medication dose.
Are there any foods or medicines I should avoid when taking XARELTO®?
Unlike warfarin, XARELTO® has no known dietary restrictions. You can still eat leafy greens and all the other healthy food you like without affecting how XARELTO® works. XARELTO® also has fewer drug-drug interactions than warfarin. But like all blood thinners, you have a higher risk of bleeding if you take XARELTO® with other medicines, like aspirin, NSAIDs, warfarin, heparin or clopidogrel, that increase your risk of bleeding.
Be sure to tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially if you take ketoconazole, itraconazole, ritonavir, lopinavir/ritonavir, indinavir, carbamazepine, phenytoin, phenobarbital, rifampin, or St. John’s wort.
How can I know if XARELTO® may be right for me?
That’s something you’ll have to talk about with your doctor. To prepare yourself for that conversation, use our Personalized Discussion Guide.
What is the most important side effect I should be aware of with XARELTO®?
If you have AFib, a prior DVT or PE blood clot, are at risk for DVT or PE, or have had hip or knee replacement surgery, you may need a blood thinner to reduce your risk of a clot or stroke. Like all blood thinners, XARELTO® can cause bleeding, which can be serious, and rarely may lead to death. Be sure to take XARELTO® exactly as prescribed, and do not stop taking XARELTO® without talking with your doctor first. You should discuss all potential benefits and risks with your doctor.
How can I save money on my XARELTO® prescription?
See your healthcare provider and ask about the Janssen CarePath Savings Program to save on your next XARELTO® prescription. Certain restrictions apply.
There are also programs for people on Medicare and people with no prescription coverage.
What if I run out of XARELTO®?
Be sure to get your prescription refilled early enough, so you never run out of XARELTO®. Skipping or stopping your medicine may increase your risk of having a DVT or PE blood clot or stroke. If you’ve been prescribed XARELTO®, you can sign up for monthly refill reminders as part of Janssen CarePath, which offers support and education resources for patients on XARELTO®.
Are there any special preparations before having a dental procedure or oral surgery?
Only the doctor who prescribed XARELTO® can tell you whether, and for how long, you may need to stop. Be sure to tell your dentist or oral surgeon that you are taking XARELTO®. He or she should talk to the doctor who prescribed XARELTO® before any dental procedure.
XARELTO® for AFib FAQs
How does XARELTO® lower my AFib-related stroke risk?
When you have AFib, your stroke risk is 5 times higher than someone without AFib. XARELTO® is a prescription medicine, a blood thinner, for people with AFib not caused by a heart valve problem. It lowers your risk of having a stroke by helping to prevent blood clots from forming.
How long will I have to take XARELTO® for my AFib?
AFib is a long-term condition that increases the risk of stroke. Only your doctor can decide how long you should take XARELTO®. Do not stop taking XARELTO® without talking to your doctor. Stopping XARELTO® increases your risk of having a stroke.
If I don’t feel the AFib in my chest anymore, can I stop taking XARELTO®?
No. You are at risk of stroke from AFib even if you don’t feel symptoms. Don’t stop taking XARELTO® unless your doctor tells you to. Stopping XARELTO® increases your risk of having a stroke. If you have to stop taking XARELTO®, your doctor may prescribe another blood thinner to help prevent blood clots from forming.
What if I forget to take XARELTO® for my AFib?
To reduce your risk of an AFib-related stroke, you should take XARELTO® once a day with your evening meal. If you miss a dose of XARELTO®, take it as soon as you remember on the same day. Take your next dose at your regularly scheduled time.
XARELTO® for DVT and PE FAQs
How does XARELTO® lower my risk of a DVT or PE?
If you’ve had a DVT or PE blood clot, you’re at greater risk of having another. XARELTO® is a prescription anticoagulant, or blood thinner, used to treat and help prevent blood clots in deep veins (such as the legs) and in your lungs. It works by blocking Factor Xa (“10a”), an enzyme needed for blood to clot.
Why does the dose change after 21 days for some people?
Clinical research done with over 8,000 people who had DVT or PE found that taking one XARELTO® 15-mg tablet twice a day with food for the first 21 days, and then one 20-mg tablet once a day with food after that, is an effective way to treat DVT and PE, and helps reduce the risk of these clots forming again.
Your doctor may start you on a different dose. You should take XARELTO® exactly as prescribed by your doctor. Do not change your dose or stop taking XARELTO® unless your doctor tells you to.
I’ve taken other steps to reduce my DVT and PE risk — can I stop taking XARELTO®?
No. Since having a prior DVT or PE increases your risk of having another blood clot, it’s very important that you take XARELTO® exactly as your doctor prescribes it, and stay on it for as long as your doctor tells you to.
What if I forget to take XARELTO® for my DVT or PE?
To reduce your risk of another DVT or PE blood clot, you should take XARELTO® with food at the same time each day.
If you miss a dose:
- and take XARELTO® twice a day: take it as soon as you remember on the same day. You may take 2 doses at the same time to make up for the missed dose. Take your next dose at your regularly scheduled time
- and take XARELTO® once a day: take it as soon as you remember on the same day. Take your next dose at your regularly scheduled time
XARELTO® for knee or hip replacement FAQs
How does XARELTO® lower my risk of blood clots after surgery?
If you’ve had hip or knee replacement surgery, you’re at greater risk for blood clots in your deep veins, such as your legs (DVT), and in your lungs (PE). XARELTO® is a prescription anticoagulant, or blood thinner, used to help prevent DVT and PE blood clots by blocking Factor Xa (“10a”), an enzyme needed for blood to clot.
How long will I have to take XARELTO® after surgery?
Most people who have hip replacement surgery will take XARELTO® 10 mg once a day for 35 days following surgery. Those who have knee replacement will usually take 10 mg once a day for 12 days. However, only your doctor can decide how long you should take XARELTO®. Do not stop taking it without talking to the doctor who prescribes it for you. Stopping XARELTO® increases your risk of having a blood clot.
What if I forget to take XARELTO® following surgery?
To reduce your risk of blood clots following hip or knee replacement surgery, you should take XARELTO® 10 mg once a day with or without food. If you miss a dose of XARELTO®, take it as soon as you remember on the same day. Take your next dose at your regularly scheduled time.