Frequently Asked Questions About XARELTO®.

Answers to frequently asked questions about XARELTO® for people with atrial fibrillation (AFib), deep vein thrombosis (DVT), or pulmonary embolism (PE), and those who’ve had hip or knee replacement surgery.

Like warfarin, XARELTO® is proven effective at reducing stroke risk in people with AFib. It’s also effective for treating and helping prevent blood clots in deep veins (such as the legs) and in the lungs.

But unlike warfarin, XARELTO® doesn’t require regular blood monitoring to check your blood- thinning level. And there are no known dietary restrictions, so there’s no need to change how you eat when taking XARELTO®.

Read more about XARELTO® vs warfarin

XARELTO® has been shown to deliver a predictable blood thinning effect. In clinical studies, involving more than 55,000 people, regular blood monitoring was not required. So regular blood tests aren’t needed to see if it’s working, check your levels, or change your medication dose.

Read more about how XARELTO® is different

If you’re eligible, you can get XARELTO® with a $0 co-pay every month with the XARELTO® Savings Card. The card is subject to a $3,400 maximum annual program benefit per calendar year with no monthly cap. Certain restrictions apply.

There are also programs for people on Medicare and people with no prescription coverage.

Read more about saving on XARELTO®

That’s something you’ll have to talk about with your doctor. To prepare yourself for that conversation, use our Personalized Discussion Guide.

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If you have AFib, a prior DVT or PE blood clot, are at risk for DVT or PE, or have had hip or knee replacement surgery, you may need a blood thinner to reduce your risk of a clot or stroke. Like all blood thinners, XARELTO® can cause bleeding, which can be serious, and rarely may lead to death. Be sure to take XARELTO® exactly as prescribed, and do not stop taking XARELTO® without talking with your doctor first. You should discuss all potential benefits and risks with your doctor.

Read more about XARELTO® side effects

Unlike warfarin, XARELTO® has no known dietary restrictions. You can eat leafy greens without affecting how XARELTO® works. XARELTO® also has fewer drug-drug interactions than warfarin. But like all blood thinners, you have a higher risk of bleeding if you take XARELTO® with other medicines, like aspirin, NSAIDs, warfarin, heparin or clopidogrel, that increase your risk of bleeding.

Be sure to tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially if you take ketoconazole, itraconazole, ritonavir, lopinavir/ritonavir, indinavir, carbamazepine, phenytoin, phenobarbital, rifampin, or St. John’s wort.

Read more about XARELTO® benefits and risks

Be sure to get your prescription refilled early enough, so you never run out of XARELTO®. Skipping or stopping your medicine may increase your risk of having a DVT or PE blood clot or stroke. If you’ve been prescribed XARELTO®, you can sign up for monthly refill reminders as part of the XARELTO® CarePath™ Support Program.

Read more about the XARELTO® CarePath™ Support Program

Only the doctor who prescribed XARELTO® can tell you whether, and for how long, you may need to stop. Be sure to tell your dentist or oral surgeon that you are taking XARELTO®. He or she should talk to the doctor who prescribed XARELTO® before any dental procedure.

Read more about XARELTO® precautions

When you have AFib, your stroke risk is 5 times higher than someone without AFib. XARELTO® is a prescription medicine, a blood thinner, for people with AFib not caused by a heart valve problem. It lowers your risk of having a stroke by helping to prevent blood clots from forming.

Read more about how XARELTO® reduces the risk of stroke

No. You are at risk of stroke from AFib even if you don’t feel symptoms. Don’t stop taking XARELTO® unless your doctor tells you to. Stopping XARELTO® increases your risk of having a stroke. If you have to stop taking XARELTO®, your doctor may prescribe another blood thinner to help prevent blood clots from forming.

Read more about taking XARELTO® for AFib

AFib is a long-term condition that increases the risk of stroke. Only your doctor can decide how long you should take XARELTO®. Do not stop taking XARELTO® without talking to your doctor. Stopping XARELTO® increases your risk of having a stroke.

Read more about taking XARELTO® for AFib

To reduce your risk of an AFib-related stroke, you should take XARELTO® once a day with your evening meal. If you miss a dose of XARELTO®, take it as soon as you remember on the same day. Take your next dose at your regularly scheduled time.

Read more about taking XARELTO® for AFib

If you’ve had a DVT or PE blood clot, you’re at greater risk of having another. XARELTO® is a prescription anticoagulant blood thinner used to treat and help prevent blood clots in deep veins (such as the legs) and in your lungs. It works by blocking Factor Xa (“10a”), an enzyme needed for blood to clot.

Read more about how XARELTO® treats and helps prevent DVT and PE

No. Since having a prior DVT or PE increases your risk of having another blood clot, it’s very important that you take XARELTO® exactly as your doctor prescribes it, and stay on it for as long as your doctor tells you to.

Read more about taking XARELTO® for DVT and PE

Clinical research done with over 8,000 people who had DVT or PE found that taking one XARELTO® 15-mg tablet twice a day with food for the first 21 days, and then one 20-mg tablet once a day with food after that, is an effective way to treat DVT and PE, and helps reduce the risk of these clots forming again.

Your doctor may start you on a different dose. You should take XARELTO® exactly as prescribed by your doctor. Do not change your dose or stop taking XARELTO® unless your doctor tells you to.

Read more about taking XARELTO® for DVT and PE

To reduce your risk of another DVT or PE blood clot, you should take XARELTO® with food at the same time each day.

If you miss a dose:

  • and take XARELTO® twice a day: take it as soon as you remember on the same day. You may take 2 doses at the same time to make up for the missed dose. Take your next dose at your regularly scheduled time.
  • and take XARELTO® once a day: take it as soon as you remember on the same day. Take your next dose at your regularly scheduled time.

Read more about taking XARELTO® for DVT and PE

If you’ve had hip or knee replacement surgery, you’re at greater risk for blood clots in your deep veins, such as your legs (DVT), and in your lungs (PE). XARELTO® is a prescription anticoagulant blood thinner used to help prevent DVT and PE blood clots by blocking Factor Xa (“10a”), an enzyme needed for blood to clot.

Read more about how XARELTO® helps prevent blood clots

Most people who have hip replacement surgery will take XARELTO® 10 mg once a day for 35 days following surgery. Those who have knee replacement will usually take 10 mg once a day for 12 days. However, only your doctor can decide how long you should take XARELTO®. Do not stop taking it without talking to the doctor who prescribes it for you. Stopping XARELTO® increases your risk of having a blood clot.

Read more about taking XARELTO® after hip or knee replacement

To reduce your risk of blood clots following hip or knee replacement surgery, you should take XARELTO® 10mg once a day with or without food. If you miss a dose of XARELTO®, take it as soon as you remember on the same day. Take your next dose at your regularly scheduled time.

Read more about taking XARELTO® after hip or knee replacement

 

XARELTO® is a prescription medicine used to reduce the risk of stroke and blood clots in people with atrial fibrillation, not caused by a heart valve problem. For patients currently well managed on warfarin, there is limited information on how XARELTO® and warfarin compare in reducing the risk of stroke.

XARELTO® is also a prescription medicine used to treat deep vein thrombosis and pulmonary embolism, and to help reduce the risk of these conditions occurring again.

XARELTO® is also a prescription medicine used to reduce the risk of forming a blood clot in the legs and lungs of people who have just had knee or hip replacement surgery.

 

WHAT IS XARELTO®?

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