What is XARELTO®?

XARELTO® belongs to a group of medicines called direct oral anticoagulants, or DOACs† for short. Like other DOACs, XARELTO® has no known dietary restrictions and no requirements for frequent blood tests.

Risk factors image

XARELTO® significantly reduces the risk of stroke in people with AFib‡ notcaused by a heart valve problem.

96%

In a clinical trial, over 96% of people who took XARELTO® remained stroke-free.§

Pill bottle

XARELTO® offers 24-hour stroke-risk reduction with just one pill a day.*

In a clinical trial comparing XARELTO® to warfarin for reducing the risk of AFib-related stroke, 99% of people taking XARELTO® did not experience bleeding into the brain, which can be serious. However, overall major bleeding was similar and gastrointestinal bleeding was about 1% higher.

*Taken with the evening meal.
†DOACs=direct oral anticoagulants.

‡AFIB=atrial fibrillation
§Rate of first occurrence of stroke was 3.8% for XARELTO® versus 4.3% for warfarin.

Take one 15-mg or 20-mg tablet
 once a day, with dinner

Tablet

Tablets shown not actual size

How do you take XARELTO®?

  • Take one tablet once a day with the evening meal
  • If you miss a dose of XARELTO®, take it as soon as you remember on the same day. Take your next dose at your regularly scheduled time
  • Do not change your dose or stop taking XARELTO® unless your doctor tells you to. Your doctor may change your dose if needed
  • Remember, there are no known dietary restrictions, unlike warfarin (Coumadin®)

Are there any side effects associated with XARELTO® in adults?

Side effects of XARELTO® :

  • Increased risk of bleeding
    • You are likely to bruise more easily and it may take longer for the bleeding to stop

Your risk of bleeding increases if you take XARELTO® with other medicines that also increase your risk of bleeding, such as:

    • Aspirin or aspirin-containing products
    • Long-term (chronic) use of non-steroidal anti-inflammatory drugs (NSAIDs)
    • Warfarin sodium( Coumadin®, Jantoven®)
    • Any medicine that contains heparin
    • Clopidogrel (Plavix®)
    • Selective serotonin reuptake inhibitors (SSRIs)
    • Serotonin norepinephrine reuptake inhibitors (SNRIs)
    • Other medicines to prevent or treat blood clots

Always tell your healthcare professional if you experience any side effects while taking XARELTO®—keeping an open and honest conversation going with your healthcare professional will help you get the best care. You can use the Doctor Discussion Guide to help inform your conversation.