Taking XARELTO® after hip or knee replacement surgery.

Most people who have hip replacement surgery will take XARELTO® 10 mg once a day for 35 days following surgery. Those who have knee replacement will usually take it for 12 days. But only your doctor can decide how long you should take XARELTO®. Take it exactly as prescribed by your doctor. Do not change your dose or stop taking XARELTO® without talking to the doctor who prescribes it for you. Stopping XARELTO® increases your risk of having a blood clot.

The XARELTO® Medication Guide has complete information on taking XARELTO® to help reduce your risk of blood clots after surgery.

XARELTO® is taken once a day, with or without food. If you miss a dose, take it as soon as you remember on the same day. Take your next dose at your regularly scheduled time.

When getting ready to leave the hospital following a hip or knee replacement, be sure that you will have XARELTO® available to avoid missing any doses. Refill your prescription of XARELTO® before you run out.


XARELTO® is a prescription medicine used to reduce the risk of stroke and blood clots in people with atrial fibrillation, not caused by a heart valve problem. For patients currently well managed on warfarin, there is limited information on how XARELTO® and warfarin compare in reducing the risk of stroke.

XARELTO® is also a prescription medicine used to treat deep vein thrombosis and pulmonary embolism, and to help reduce the risk of these conditions occurring again.

XARELTO® is also a prescription medicine used to reduce the risk of forming a blood clot in the legs and lungs of people who have just had knee or hip replacement surgery.



Important Safety Information