PAD Treatment Options

While peripheral artery disease (PAD) is progressive and cannot be cured, there are treatment options that can help slow or stop its progression, reduce symptoms like intermittent claudication, and reduce your risk for cardiovascular events like heart attack, stroke, or serious blockages in the legs that could lead to amputation.

Surgical and nonsurgical procedures

The following may be performed to restore blood flow in a blocked artery:

  • Angioplasty opens a blocked artery by inflating a tiny balloon inside the blockage
  • Stent implantation permanently props open a blocked artery with a tiny, wire mesh tube that is placed during an angioplasty
  • Atherectomy uses a sharp blade and a catheter to collect and remove plaque from inside a blocked artery
  • Peripheral artery bypass graft surgery reroutes blood around a completely blocked artery using a man-made blood vessel or a blood vessel from another part of your body

While the above procedures are often necessary and even lifesaving, they are not a permanent solution to your PAD, which is why it’s important to keep taking any medicines your healthcare professional has prescribed.

Prescription and nonprescription antiplatelet blood thinners

An antiplatelet is one type of blood thinner that works by helping to keep platelets (which are a type of blood cell) from sticking together. Examples include:

  • Aspirin
  • Clopidogrel (Plavix®)

Dual antiplatelet therapy (DAPT)

DAPT is aspirin plus one other antiplatelet medicine, and is typically prescribed to help prevent future serious cardiovascular events.

Prescription anticoagulant blood thinners

Anticoagulant blood thinners like XARELTO® are another type of blood thinner that works by slowing down the blood’s clotting process. XARELTO® can be added to aspirin to help further reduce the risk for heart attack, stroke, and cardiovascular death.

XARELTO® is the only anticoagulant blood thinner approved to help further reduce the risk for heart attack, stroke, and cardiovascular death when added to aspirin.

Other prescription medicines

These may be prescribed to address other health conditions or risk factors that contribute to the progression of your PAD. Examples include:

  • Medication to help lower your blood pressure
  • Medication to help lower your cholesterol
  • Medication to control blood sugar in people with diabetes

Lifestyle changes

While no medicine or procedure can completely rid your arteries of plaque, it is possible to slow the progression of your PAD by managing your overall health. In addition to taking any other medicines your doctor has prescribed, like medicines for high blood pressure or high cholesterol, it’s also important to make certain lifestyle changes, including:

  • Quitting smoking
    • Studies show that one year after quitting, your risk for developing coronary artery disease (CAD)—which is related to PAD—drops by about 50%. 15 years after quitting, your risk is the same as someone who has never smoked.
  • Switching to a heart-healthy diet
    • Find tips that make eating well simple and straightforward.
  • Adding physical activity
    • When supervised by your healthcare professional, an exercise program that includes walking can improve your PAD symptoms by increasing blood to your limbs, strengthening your heart, and helping your body use oxygen more efficiently.