Managing Risk for
Recurrent Pulmonary Embolism

If you’ve completed at least six months of treatment for a pulmonary embolism (PE), it’s important to understand that certain risk factors—primarily ones that you can’t change or control—may mean you have an ongoing risk for recurrent pulmonary embolism. People with recurrent PE have a high risk for having multiple PE blood clots in the future.

PE risk factors that can contribute to multiple pulmonary embolisms

If you stop taking a blood thinner:

After 5 years,
chance of another

After 10 years,
chance of another

Up to
of future PE or DVT
blood clots result in a
fatal PE

  • A previous PE or deep vein thrombosis (DVT)
  • Having certain blood disorders that make your blood more likely to clot (eg, factor V Leiden, a mutation of one of the clotting factors involved in normal blood clotting)
  • Older age

Your healthcare professional will evaluate your risk factors and may recommend that you continue taking a blood thinner like XARELTO®. This is important because people who have had a PE or DVT and stop taking blood thinners have an even higher chance of having another blood clot.

XARELTO® vs aspirin to help reduce your risk for recurrent PE

If your healthcare professional believes you are at continued risk, the question becomes how to reduce your chance of having another PE. Some people may be prescribed aspirin to help prevent them from having another event. However, in a clinical trial with at-risk people who had already completed at least six months of initial treatment for a PE, XARELTO® was shown to be superior to aspirin at reducing their risk for future PEs.

  • The risk of another PE happening again was significantly lower with XARELTO® 10 mg than with aspirin*
  • XARELTO® is the only blood thinner with major bleeding rates proven to be as low as those of aspirin*

*After completion of initial treatment lasting at least 6 months

Talk to your healthcare professional about XARELTO® vs aspirin for reducing your risk of future PE events. Need help asking the right questions? Create your personalized conversation starter and bring it to your next appointment.