What is XARELTO®?
XARELTO® belongs to a group of medicines called direct oral anticoagulants, or DOACs† for short. Like other DOACs, XARELTO® has no known dietary restrictions, no requirements for frequent blood tests, and few drug interactions.
XARELTO® significantly reduces the risk of stroke in people with AFib not caused by a heart valve problem.
In a clinical trial, over 96% of people who took XARELTO® remained stroke-free.‡
XARELTO® offers 24-hour stroke-risk reduction with just one pill a day.*
In a clinical trial comparing XARELTO® to warfarin for reducing the risk of AFib-related stroke, 99% of people taking XARELTO® did not experience a serious bleed, such as bleeding into the brain. However, overall major bleeding was similar and gastrointestinal bleeding was about 1% higher.
*Taken with the evening meal.
†DOACs = direct oral anticoagulants.
‡Rate of first occurrence of stroke was 3.8% for XARELTO® versus 4.3% for warfarin.
Take one 15-mg or 20-mg tablet once a day, with dinner
How do you take XARELTO®?
- Take one tablet once a day with the evening meal
- If you miss a dose of XARELTO®, take it as soon as you remember on the same day. Take your next dose at your regularly scheduled time
- Do not change your dose or stop taking XARELTO® unless your doctor tells you to. Your doctor may change your dose if needed
- Remember, there are no known dietary restrictions, unlike warfarin (Coumadin®)
Are there any side effects associated with XARELTO® in adults?
Side effects of XARELTO®:
Increased risk of bleeding
- You are likely to bruise more easily and it may take longer for the bleeding to stop
Your risk of bleeding increases if you take XARELTO® with other medicines that also increase your risk of bleeding, such as:
- Aspirin or aspirin-containing products
- Long-term (chronic) use of non-steroidal anti-inflammatory drugs (NSAIDs)
- Warfarin sodium (Coumadin®, Jantoven®)
- Any medicine that contains heparin
- Clopidogrel (Plavix®)
- Selective serotonin reuptake inhibitors (SSRIs)
- Serotonin norepinephrine reuptake inhibitors (SNRIs)
- Other medicines to prevent or treat blood clots
Always tell your healthcare professional if you experience any side effects while taking XARELTO®—keeping an open and honest conversation going with your healthcare professional will help you get the best care. You can use the Doctor Discussion Guide to help inform your conversation.