What is XARELTO®?
XARELTO® belongs to a group of medicines called direct oral anticoagulants, or DOACs for short. Like other DOACs, XARELTO® has no known dietary restrictions and no requirements for frequent blood tests.
XARELTO®, in combination with low-dose aspirin,‡ is the only drug in its class§ indicated to help reduce the risk of heart attack, stroke, or cardiovascular death in adults with CAD.
In fact, in a clinical trial, almost 96% of adults with CAD taking XARELTO® 2.5 mg twice daily, in combination with low-dose aspirin, did not have a heart attack, stroke, or die from a cardiovascular event.||
Remember, all blood thinners come with a risk of bleeding. Around 3% of people taking XARELTO® 2.5 mg twice daily in combination with low-dose aspirin experienced a major bleeding event, such as bleeding into the brain, compared to around 2% of people taking low-dose aspirin alone.
‡Low-dose aspirin = 75 mg–100 mg once daily.
§Direct Oral Anticoagulant (DOAC).
||The rate of the first event like a stroke, heart attack, or cardiovascular death was 4.2% for people taking XARELTO® plus aspirin vs 5.6% for aspirin alone. Patients were followed for an average of 23 months.
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Talk to your doctor about XARELTO®
Use this guide to discuss the risks of cardiac events due to CAD with your doctor, and whether XARELTO® may be right for you.
Take one XARELTO® 2.5 mg tablet twice daily with or without food in combination with low-dose aspirin (75 mg-100 mg) once daily
Tablets shown not actual size
How do you take XARELTO®?
- Take XARELTO® 2.5 mg twice daily with or without food in combination with aspirin 75 mg–100 mg once daily as instructed by your healthcare professional
- If you miss a dose of XARELTO®, take your next 2.5 mg dose at your regularly scheduled time
- Remember, there are no known dietary restrictions, unlike warfarin (Coumadin®)
Are there any side effects associated with XARELTO® in adults?
Side effects of XARELTO®:
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Increased risk of bleeding
- You are likely to bruise more easily and it may take longer for the bleeding to stop
Your risk of bleeding increases if you take XARELTO® with other medicines that also increase your risk of bleeding, such as:
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- Aspirin or aspirin-containing products
- Long-term (chronic) use of non-steroidal anti-inflammatory drugs (NSAIDs)
- Warfarin sodium (Coumadin®, Jantoven®)
- Any medicine that contains heparin
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- Clopidogrel (Plavix®)
- Selective serotonin reuptake inhibitors (SSRIs)
- Serotonin norepinephrine reuptake inhibitors (SNRIs)
- Other medicines to prevent or treat blood clots
Always tell your healthcare professional if you experience any side effects while taking XARELTO®—keeping an open and honest conversation going with your healthcare professional will help you get the best care. You can use the Doctor Discussion Guide to help inform your conversation.
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Getting started with XARELTO®?
Discover information about getting started with XARELTO®, savings options, and your condition—all in one helpful starter kit.