Understanding CAD and blood clots

Coronary artery disease (CAD) is the most common heart disease in the US and is the leading cause of death for both men and women, claiming over 370,000 lives each year. If you’re living with CAD, you are at a higher risk for developing a blood clot.

How does CAD increase the risk for blood clots?

People with coronary artery disease have an underlying risk for blood clots that can cause a heart attack or stroke. This is because some plaques (fatty deposits), in addition to reducing blood flow through the arteries, can rupture. A ruptured plaque triggers your body’s blood-clotting response.

A clot forms around the rupture site, creating a blockage and cutting off blood flow and oxygen to your heart. This is what causes a heart attack. A stroke can occur if a blood clot causes blood flow to your brain to be restricted. Both of these events can be life threatening.

How does CAD affect the body?

Click or tap on a number, or one of the arrows, to learn more about how blood clots can cause a stroke.

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What can you do to help prevent blood clots due to CAD?

Aspirin may reduce your risk of serious cardiovascular events due to blood clots, but further reduction is possible with XARELTO®.

  • A large study of almost 40,000 people, including those with peripheral artery disease (PAD) or coronary artery disease (CAD), showed that even though more than half were taking aspirin, the number of heart attacks, strokes, and cardiovascular deaths more than doubled over a 2-year period.*
  • Adding XARELTO® to your daily aspirin helps reduce the risk of heart attack, stroke, and cardiovascular death in people with CAD.

*According to data from the REACH Registry

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Talk to your doctor about XARELTO®

Use this guide to discuss the risks of cardiac events due to CAD with your doctor, and whether XARELTO® may be right for you.