What is XARELTO®?

XARELTO® belongs to a group of medicines called direct oral anticoagulants, or DOACs for short. Like other DOACs, XARELTO® has no known dietary restrictions, no requirements for frequent blood tests, and few drug interactions.

XARELTO® helps reduce the risk for blood clots and the life-threatening events they can cause.

XARELTO® slows your body's ability to clot by selectively blocking one of the clotting factors found in your blood — an enzyme called Factor Xa ("10a").

Take one 10-mg tabletonce a day, with or without food

nsh dosing

Tablets shown not actual size

How do you take XARELTO®?

  • If you miss a dose of XARELTO®, take it as soon as you remember on the same day. Take your next dose at your regularly scheduled time.
  • Take one 10-mg tablet once a day, with or without food.
  • Remember, there are no known dietary restrictions, unlike warfarin (Coumadin®).

A few things to remember:

  • Do not change your dose or stop taking XARELTO® unless your healthcare professional tells you to. Stopping XARELTO® increases your risk of having a stroke.
  • Tell all the healthcare professionals you see, including your dentist, that you’re taking XARELTO®. They should talk to the healthcare professional who prescribed XARELTO® before any surgical, medical, or dental procedure. Your doctor will tell you when to stop taking XARELTO® and when to start taking XARELTO® again after your surgery or procedure.
  • Tell your healthcare professional about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What is the risk of a blood clot during and after a hospital stay?

When you are in the hospital, limited movement and other risk factors can mean your blood flow is slower than normal, which increases the chance that a DVT or PE blood clot will form. What's more, hospitalization for some illnesses can increase your risk more than 10 times:

  • Pneumonia
  • Stroke (particularly ischemic stroke)
  • Heart failure

The risk for DVT and PE blood clots doesn’t always go away once your hospital stay is over. In fact, the risk for developing a DVT or PE is especially high during the first weeks after being discharged from the hospital.

Over 8 million people at risk for hospital-related DVT and PE blood clots

How common are DVT and PE blood clots after hospitalization?

Each year, more than 8 million Americans are at risk for experiencing DVT or PE blood clots that are related to a hospital stay.

  • About half of all DVT and PE blood clots are related to being hospitalized, and these blood clots typically occur within the first 3 months of hospital stay
  • According to a study, 86% of people who developed a DVT or PE within 3 months after discharge ended up back in the hospital

*According to the Centers for Disease Control and Prevention (CDC).

Study conducted from 2005 to 2010.

What is a DVT?

A deep vein thrombosis, or DVT, is a blood clot that occurs in a vein, often when blood flow slows down. For example, if you have to spend a lot of time in bed because of a hospitalization, your blood flow could slow down enough to form a clot.

How does a DVT blood clot form?

Watch this short video to see how a DVT forms and the symptoms it can cause.

What are the symptoms of a DVT?

  • Swelling of the leg or affected area
  • Pain or tenderness at rest or when standing or walking
  • Skin that is warm to the touch
  • Skin that is red or discolored

Learn More About DVT

What is a PE?

A pulmonary embolism, or PE, is a potentially life-threatening event that happens when a DVT blood clot breaks off and travels through the bloodstream to the lungs.

How does a blood clot become a PE?

Watch a short video to see how a DVT blood clot can cause a PE, and the symptoms to look out for.

What are the symptoms of a PE?

  • Unexplained shortness of breath
  • Rapid breathing
  • Chest pain that may worsen with coughing or deep breathing
  • Coughing or coughing up blood
  • A rapid or irregular heartbeat
  • Feeling lightheaded or passing out

Learn More About PE

Are there any side effects associated with XARELTO® in adults?

Side effects of XARELTO®:

  • Increased risk of bleeding
    • You are likely to bruise more easily and it may take longer for the bleeding to stop

Your risk of bleeding increases if you take XARELTO® with other medicines that also increase your risk of bleeding, such as:

    • Aspirin or aspirin-containing products
    • Long-term (chronic) use of non-steroidal anti-inflammatory drugs (NSAIDs)
    • Warfarin sodium (Coumadin®, Jantoven®)
    • Any medicine that contains heparin
    • Clopidogrel (Plavix®)
    • Selective serotonin reuptake inhibitors (SSRIs)
    • Serotonin norepinephrine reuptake inhibitors (SNRIs)
    • Other medicines to prevent or treat blood clots

Always tell your healthcare professional if you experience any side effects while taking XARELTO®—keeping an open and honest conversation going with your healthcare professional will help you get the best care.

man with bicycle

How does XARELTO® work?

XARELTO® slows your body's ability to clot by selectively blocking one of the clotting factors found in your blood—an enzyme called Factor Xa ("10a").