XARELTO® is a blood thinner that treats and helps prevent blood clots that are related to certain conditions involving the heart and blood vessels.

What are the types of blood thinners?

There are two types of blood thinners—antiplatelets and anticoagulants. Contrary to their name, blood thinners do not actually thin your blood. Both types affect how blood normally clots in your body, but they do it in different ways:

  • Antiplatelets

    Antiplatelets lower your blood’s ability to clot by preventing platelets—cell fragments in your blood—from sticking together and forming clots. Examples include aspirin, clopidogrel (Plavix®), prasugrel (Effient®), and ticagrelor (Brilinta®).

  • Anticoagulants

    Anticoagulants lower your blood’s ability to clot by stopping specific proteins and enzymes, also known as clotting factors, from doing their job to help blood clots form.

XARELTO® is an anticoagulant blood thinner

XARELTO® belongs to the category of latest-generation blood thinners commonly called DOACs, or direct oral anticoagulants. One thing that makes DOACs different from older blood-thinning medications is that they affect fewer of the proteins and enzymes that help blood clots form. These proteins and enzymes are called clotting factors, and XARELTO® targets just one—Factor Xa (“10a”).


See how XARELTO® works to help reduce your risk of blood clots.

XARELTO® has been prescribed more than 40 million times in the US alone.

Janssen—Your Partner for Cost Support

At Janssen, we don’t want cost to get in the way of treatment you need. We can help you explore options to lower your out-of-pocket cost for XARELTO®.

XARELTO® benefits

  • No known dietary restrictions while on XARELTO®

    XARELTO® doesn’t interact with vitamin K like warfarin does. This means you can enjoy leafy green vegetables and other foods high in vitamin K whenever you like—without it interfering with your medication.

  • XARELTO® usage doesn’t require regular blood testing

    Studies show that the effect of XARELTO® on your body’s blood-clotting function is the same regardless of age, race, weight, sex, or dietary changes. If you take XARELTO®, regular blood tests are not needed to see if XARELTO® is working, to check your blood-thinning levels (international normalized ratio, or INR), or to change your medication dose.*

    *Certain patients with impaired kidney function may be monitored by their healthcare professional and have their dose adjusted as necessary.

  • XARELTO® dosing doesn’t require frequent adjustments

    While the dosage is different depending on why you are taking XARELTO®, most people will start and stay on the same dosage. Exceptions include people with kidney problems whose condition may require a dosage adjustment, or people taking XARELTO® to treat a DVT or PE, since the dose changes after 21 days of treatment.

To learn more about how XARELTO® treats and helps prevent blood clots related to a specific condition, select below:

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XARELTO® Side Effects and Benefits

Learn more about the side effects of XARELTO® and how your healthcare professional can help assess the risks and benefits.

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XARELTO® vs Warfarin

See how XARELTO® compares to warfarin.

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